According to a new study, regardless of the Body Mass Index (BMI), human beings with relatively hidden fat in muscles have a higher risk of death or hospitalization due to heart disease.
The result is tHe is a marker of heart health, and BMI’s inappropriate Potential risk factors for cardiovascular disease that guarantee further research.
“If you know that muscle fat increases the risk of heart disease, there is another way to identify people with high risk regardless of the body mass index.” Say Co -author, Viviany Taqueti, Brigham and Women’s Heart Laboratory Director.
The author pointed out that the health impact of fat muscles was still not well understood, but it was associated with insulin resistance and type 2 diabetes among other diseases. This is the most thorough study of the effects of the heart disease of fat muscles so far, they say.
In addition to revealing this link, this study emphasizes the limitations of metrics such as BMI when evaluating heart disease risks.
“Obesity is now one of the biggest global threats to cardiovascular health, but the body mass index, which is our main indicator to define obesity and critical values for mediation, is still a controversial and flawed marker. ” Explain Taqueti
“This is especially true for women who can reflect ‘positive’ fats with higher body mass indexes.”
Of course, all body fat needs body fat. Of course, all body fat is required, including a small sediment built into the skeletal fiber called IMAT.
Muscle liver fat is present in most muscles, but the amount varies from person to person, and it tends to increase with age. Sometimes too much fat in parenting is accumulated between the skeletal muscles and is known as fat penetration or musculoskeletal.
In previous studies, high levels of IMAT Insulin resistance and Metabolic syndromefurthermore Loss of power and Mobility. But it is not known about the IMAT, including how it affects cardiovascular health.
Taqueti and her colleagues are muscle quality Coronary microvascular dysfunction (CMD) -The state of damage to a small blood vessel that provides the heart -and other cardiovascular disease.
“In our study, we analyze muscles and different types of fats, how the body composition can affect the ‘micro circulation’ of a small blood vessel or heart of the heart, heart failure, heart attack and death future risk” Say.
In this study, all 669 subjects, Brigham and Women’s Hospital had no signs of chest pain or breathing, but there were no signs of obstructive coronary arteriosclerosis. About 70 %were women, 46 %were not white, and the average age was 63 years old. report.
The researchers examined the heart of each patient with a scanning of the Heart Electronics release tomography/computed tomography (PET/CT) scan. In addition, the CT scan is used to reveal body composition and measure the amount and position of fat and muscles.
Their analysis was related to the measurement Fat muscle fraction -The ratio of muscle liver and skeletal muscles and mousse mile fats.
Researchers have been killed or hospitalized for about six years with subjects with heart attacks or heart attacks.
Patients with higher IMAT levels were more likely to have CMDs, and had a high risk of death or hospitalization due to heart disease.
The 1 % increase in Fatty Muscle Fraction had a 2 % higher risk of CMD, and the risk of major side effects was 7 % higher regardless of BMI and other known risk factors.
Patients with evidence of excessive IMAT and CMD are particularly in danger and have much more risk of death, heart attack and heart failure.
The higher the muscles, the lower the risk. Storing fat elsewhere in the body, as shown under the skin, did not increase the risk.
“Compared to subcutaneous fat, fat stored in muscles can contribute to inflammation, change glucose metabolism, and can lead to insulin resistance and metabolic syndrome.” Taqueti Say. “In turn, this chronic insult can damage the blood vessels, including the supply of the heart and the heart muscles itself.”
This study is recognized by the author and the other two researchers Accompanying editing.
Future studies should dig deeper and deepen the connection between fat muscles and heart disease and investigate how to save life using this information.
This study was published later. European Heart Journal.
