It is not a secret that women and men experience differently, Difference in pain perception. Hormones are known to affect pain sensitivity, the body structure affects the density of the pain receptor, and psychological and social factors play an important role in how pain is recognized and expressed.
It is surprising that all these factors have been kept in mind, and most of the pain studies have historically ignored gender differences. As a result, many studies have missed the opportunity to analyze or report these differences. In pain studies, the impact of this sexual prejudice is clear. International Association for Pain Research.
Fortunately, research is improving. Today’s research is asking more questions and contains female participants in preclinical and clinical studies. recent study Published in San Francisco, California University scienceMainly, female hormone estrogen and progesterone show how it helps to suppress pain by stimulating the production of opioids in the body.
The role of the immune system in pain
To understand pain, you need to recognize an important role in the immune system. T cells, the type of white blood cells, are known to affect pain amplification, although the exact mechanism is still not fully understood.
The new study focuses on the T-cell type of T-type called T-regs recently discovered. These cells have been found to reduce inflammation and are rich in the protection layer of the spinal cord known as mening. According to this study, the T-reg is used to communicate with neurons near the skin using a mening. To better understand how T-regs functions, researchers used the proven methods. They used toxins to remove cells.
Read more: Chronic pain makes you think differently
Female hormones cause analgesics production
Disabling T-Regs has an immediate effect. Compared to male opponents, female mice are much more sensitive to pain and emphasize the importance of these immune cells in managing the pain of the female.
Further surveys show that the primary female hormones, estrogen and progesterone, allow T-regs to generate the body’s natural painkillers (opioid-like substance enkephalin).
“It is rare that the fact that these cells, driven by estrogen and progesterone, have gender -dependent effects, are not related to immune function. press release.
Future of pain management
This discovery makes the research team excited about the future of pain treatment. They hope to continue to explore the exact mechanisms of this new path, which leads to more effective pain treatment and raising awareness of the importance of studying the basic mechanism of women’s pain management.
One potential approach is to directly target T-Regs to increase the production of analgesic Enkeepalin, which will ultimately help both women and men.
Co -author Allan Basbaum said, “If this approach is successful, it can change almost 20%of Americans who have experienced chronic pain that is not treated properly.
Understanding the role of sex hormones in pain control can help doctors better support for women, especially those who are experiencing menopause. This knowledge can lead to more personalized pain treatment in the future.
This article does not provide medical advice and should only be used for the purpose of providing information.
Read more: FDA
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Jenny is excellent for translating complex scientific concepts, from medical innovation and pharmacological discoveries to the latest nutrition after working as a biotechnology research assistant in three labs in three countries. Her interests are expanded to topics such as human evolution, psychology and quirky animal stories. If she is not immersed in a popular science book, she will find a wave that catches Vancouver Island on her long board.
