A growing number of lesser-known compounds found in the cannabis plant may one day provide CBD.Cannabidiol) making money.
How are first-in-human clinical trials tested? Cannabigerol The effects of (CBG) on anxiety and stress showed encouraging results in 34 healthy users.
CBG recently said,The mother of all cannabinoids“Because it can be be metabolized quickly It is divided into CBD and THC (tetrahydrocannabinol). THC is the psychoactive ingredient contained in cannabis.
In a recent trial tThe man who took the hose tincture People who took CBG reported significantly reduced anxiety and stress within an hour of taking it compared to those who took a placebo.
What surprised the researchers was that participants who took CBG performed slightly better on verbal memory tests.
Previous research We found cannabis products containing THC. reduce Verbal memory scores also improved to a similar level.
However, like CBD, CBG does not produce the same intoxicating effects as THC.
Carrie Cuttler, a psychologist at Washington State University, and her colleagues were intrigued by their results, but The growing hype around the CBG market As with CBD, it’s outpacing the actual science.
“It would also be interesting to investigate whether CBG could counteract the detrimental effects of THC on verbal memory, as CBD was initially claimed to do. However, several attempts to replicate these results have failed.” write In a paper published by the author.
CBD is the most popular, non-addictive cannabinoid ever discovered and has therapeutic potential. UnknownAnxiety, and perhaps chronic pain. But despite the fact that many CBD products are often marketed as panaceas, the scientific evidence for many of these claims is lackluster or nonexistent.
This is especially true for CBG.
“We should avoid claims that CBG is a miracle drug.” Warn Cutler.
“It’s new and exciting, but replication and further research are important.”
CBG is found only in trace amounts in the cannabis plant and has historically been of lesser importance compared to THC and CBD.
Out of About 100 Although it is one of the most potent cannabinoid compounds scientists have ever discovered in plants, CBG has shown some of the most promising results in preclinical studies.
~ inside Some animal studiesCBG shows potential anti-inflammatory and analgesic effects. It also Reduce seizures In a mouse model of childhood epilepsy.
However, only two human clinical trials have been published to date on the effects of CBG, neither of which looked at its potential in treating anxiety.
A recent experiment by Cutler and her colleagues attempts to fill that gap.
In the first part of the experiment, half of the participants took a placebo, while the other half took CBG tincture. No one, not even the researchers, knew who was taking what.
After taking the tincture, participants rated their mood, stress, anxiety, and other variables (such as feeling drunk or side effects like dry eyes or mouth). They did this 20, 45, and 60 minutes after ingestion.
The experiment was repeated a week later, with the placebo participants given the tincture, and vice versa.
The experiment was conducted remotely via Zoom, and participants taking CBG only scored lower on a general anxiety test, but not on other, more specific anxiety tests.
Despite these limitations, early research on CBG’s potential to treat anxiety and stress suggests: Preliminary investigation Written by some of the same authors.
In a survey, most CBG users said they took the extract to manage their anxiety, and many of those surveyed said CBG was more effective than traditional medications.
About a third of respondents reported using CBG for depression, but the current trial found that it had no significant effect on participants’ mood.
This may be because the doses of CBG used in the experiments were low, or because the study population was small, resulting in low rates of depression.
“CBG is growing in popularity, and more and more producers are making bold, unproven claims about its effects.” Say Cutler.
“Our study is one of the first to provide evidence to support some of these claims, helping to inform both consumers and the scientific community.”
The study was published in scientific report.
