Catalonia Maria Brice In August 2024, she died at a grand age of 117 years old, and she was officially the oldest living person in the world.
In order to determine how Maria collected many birthdays, the teams led by researchers from the Josep Carreras REUKEMIA Research Institute in Spain have performed a comprehensive analysis of everything from genes to protein, microorganisms, to metabolism.
Their reports that have not yet reviewed their colleagues have made a glimpse of the cellular machine.
Mary is A Super Sentenian -This person who reaches 110 years old or uRPASS -it is quite accomplished. Only one out of 10 people in a century manages for 10 years.
The researchers have used a variety of analytical techniques and interviews to discover that Mary has checked a lot of recommended boxes regarding longevity and healthy aging.
She had a mental, social, physical and physical lifestyle, for example, had a good time with her family and friends. All factors known to prevent dementia. Mary also adhered to the longer life expectancy.
One mentioned by the researchers was the love of Mary’s yogurt. Researchers believe that Super Centennian’s choice of diet helped to encourage healthy intestinal bacteria.
“Microorganisms are important not only to compose metabolites of our body, but also to determine inflammation, intestinal permeability, cognitive, bone and muscle health.” write Researchers are in published papers.
The change of our DNA has long been considered important for our death rate. Mary has a gene associated with stronger immune system, protection of heart disease and reduction of cancer risks.
I also saw this study DNA methylation; Chemical display mechanism that affects the way the genes are expressed. Since this mechanism is affected by the stress of the environment, it is often used to measure the passage of life trials in the content described as biological era.
“Surprisingly, all the distinct algorithms of age based on DNA methylation have calculated the same results.” write researcher.
“Our beginner has seen a much younger biological era than her actual chronology, which occurred in three analyzed organizations.”
The other factors emphasized by the researchers were Mary’s very efficient metabolism, causing lower levels of ‘bad’ cholesterol and higher levels of ‘good’ cholesterol and low levels of inflammation (protecting multiple health problems).
Mary himself It is clear that her longevity is left as “an orderly life and a pleasant surrounding environment”, but there are many factors in the workplace. Most of us do not reach 117, but this study helps to understand how the body can get the best opportunity to agree without damage or disease.
“The paintings from our studies show that the extremely advanced age and healthy health are not inherently connected, and both processes can be distinguished and dissected at the molecular level.” write researcher.
This study is not yet posted in a fellow review journal, but can be used on the Preprint server. Biorxiv.
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